Our veterinary staff provide the utmost care for the animals used in your experiments. We have dedicated clean vivarium suites to suit both non-radioactive and radioactive studies.
We maintain animals in precisely regulated vivariums—controlling temperature, humidity, vibration, and light cycles—to minimize stress and protect the integrity of your results.
We are cognizant of the location and spacing of your animals, particularly for efficacy studies, ensuring minimal cross-talk between cages and animals.
The oversight and care of your animals is covered 24/7 by our veterinary staff.
Our biology team offers expert support in the establishment of murine/human CDX and PDX mouse and rat models.
We have experience generating subcutaneous, orthotopic, and metastatic cancer models through various injection techniques. We also implant murine or human tumor tissue subcutaneously or orthotopically. Please inquire about our genetic engineered mouse models.
Inject murine/human cells IV, subcutaneously, or orthotopically. We source cell lines from several reputable suppliers.
Implant tumor tissue subcutaneously or orthotopically. We are constantly expanding our PDX bank - please inquire about which diseases and biomarkers that we have.
Our imaging team has decades of experience designing and executing quantitative preclinical imaging studies, particularly for oncologic radiopharmaceutical theranostic programs.
Our primary objective is to generate robust, rigorous and reproducible quantitative data so you can be confident in the biodistribution, safety, efficacy and dosimetry of your radiopharmaceuticals.
Imaging of companion radionuclides such as 64Cu, 18F, 68Ga, 124I, 52Mn, 44Sc, 86Y, 89Zr
Quantitative & qualitative analysis
Biodistribution
Dosimetry
Drug screening
Kinetic modeling
Imaging of theranostic radionuclides such as 67Cu, 111In, 123I, 131I, 177Lu, 203Pb, 161Tb, 99mTc
Quantitative & qualitative analysis
Biodistribution
Dosimetry
Drug screening
Kinetic modeling
Semi-quantitative & qualitative
Monitor tumor growth and metastasis
Assess efficacy and treatment response
Subject-selection
Remember,
garbage in=garbage out.
Rest assured, our team of medical physicists and nuclear medicine imaging experts ensure our systems are calibrated and corrected so that your data is accurate. In addition to routine scanner calibration, we have employed custom-developed and validated processes, like our partial volume correction (PVC) protocols, so that your dosimetry data is accurately guiding preclinical and clinical decisions.
Already acquired imaging/bioD data and want to calculate dosimetry?
Send us the unanalyzed or analyzed data.
We run ex vivo mouse/rat model-based dosimetry, image-based dosimetry and/or OLINDA-based estimates.
